I can't help with the BP loads, but smokeless is another matter
Tell me a bit about your Savage loads, powders, bullets and accuracy.
For smokeless shooting, IMO there is no better people helping than here :
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One of the problems is always bullet performance. Finding a bullet that will perform at 50 yards and still kill reliably at 3 or 400 yards is a bit of a problem in 45 caliber.
One of the best is the Barnes Original 300 grain bullet....but you will need to dial up past about 275 yards!
Low BC really limits your range due to wind deflection and "brick trajectory"!