It depends on how you define 'worth it' and...
The individual barrel: condition, rounds fired, throat, "break in', cold bore vs. warm bore difference.
- Take off barrels are $50 to $100 or so and of course available immediately.
- Rack barrels, prefit (in-stock, ready to ship) $200ish to around $400ish of course available immediately
- Custom, the sky is the limit.
Then there is the gunsmith fees. More for 'blanks'. My smith to install a take off or prefit charges very little. Sometimes he will do it 'while I wait'. YMMV.
Truing is an issue because if your smith chases the barrel threads, take off and prefit barrels could pose a problem. I'd specify not to chase the threads only true the face and bolt race.
I have not so far tried it. I was gonna get a 300RUM barrel as a 'spare' but it went before I saw the ad.
With my smith, no truing, used take off barrel at $50 it would probably cost a total of $100 as long as I brought only the barreled action.
My Pac-Nor barrels cost more than the original rifle but shoot very well.
How do you define 'worth it'