1:9.5 twist will most likely stabilize the 180VLD, although there is only one way to know for sure....shoot it!
In terms of loading the bullet up close to the lands and still being able to fit in the mag, I would lean towards probably not. Most factory rifles have very long throats. As a result, you've got to stick that bullet way out there to get close to the lands. Far enough out that it might not fit into the mag.
I had a factory Remington 308 (
My 308 1k Rifle - The Evolution Continues!) and loaded the 175VLD in it. In order to load the bullets close to the lands, they would not fit in the magazine.
Unless you have some other intended use than longrange hunting, single loading your rifle does not really put you at a disadvantage.