Ive got 3 Tikkas and 2 Sakos all have Optiloks and are sweet as!
Never had any problems with them really but, I have found that on the bigger Magnums like 300WSM and my 375 H&H that the screws can do with a tweak once they get settled in, Ive only had to do this on NEW sets, once they been used they're fine.
Make sure that you tighten them evenly too, 1/4 turn then move to the diagonal screw 1/4 turn and so on, moving from the front to back rings, dont tighten back one up fully them move on to the front.
Share the love between the two
Hope this helps