You will be well pleased with those 100 gr Pro Hunters. I have killed hundreds of white tail deer with Sierra bullets in most every caliber between 6mm through 45 cal and never had any reservation about using them. I also have found that the 4350s just plain work in 243s.
I have a custom 25-06 with a Shilen SS barrel that will not shoot boat tail bullets either. It sure will shoot a flat base though. 117 Sierra Pro Hunters shoot bug holes and drop deer like you jerked the ground out from under them.