I've never had any luck with Hornady bullets providing stellar groups in my rifles but some guy do very well with them so maybe Lerch has touched on a possible difference in results.
I tried their 139 gr Interbond in two 7mm Rem Mags and the group sizes were consistently 2-3 times larger than I achieved with Nosler 140 gr Accubonds and BTs. The first box of Hornady Interbonds had a bunch of crooked plastic tips on them. I didn't notice them until I'd shot about 1/2 of the box of 100. So I sent them back to Hornady and they mailed me a new box of 100. Well 26 of those 100 pack of bullets had crooked tips too. And several of the plastic tips were loose. In fact one tip fell off when I picked the bullet up out of the box. Didn't give me a lot of confidence in Hornady's manufacturing process or quality control. And it wasn't just a fluke with my 7mm Hornadys. I told two guys at work about my experience and then brought my bullets in and showed them to them. So they go home and bring in some of the .308 & .338 Hornady Interbonds that they had on their reloading benches and their plastic tips were also crooked
If you're trying to load Hornady Interbonds, I'd pull the plastic tips off them first. Either that or load them butt end first!
I guess that would make for a butt-ugly cartridge that shot butt-ugly bad! Seriously though, they were a joke.
But like I said, a number of folks report good results, which I can't explain based on my experiences. FWIW, I gave up on Hornady bullets after I returned the box with the crooked tips and then they turned around and sent me a new replacement box which ran a 26% crooked tip rate. A lot of good that did me. You'ld have thought they'd have at least looked at the bullets before they sent them off to me.
No crooked plastic tips on my Nosler's so far.