Well you can take it for what it's worth, but here is a plate we have at 500yds.
If you look you will see multiple impacts which have been painted over. These are mostly from various "hunting bullets" out of a 300 RUM, including Sorrico's, Bonded Cores, Interbonds, and the major crators which aren't painted Berger 210gr VLD's. All of the other bullets weighed from 117grs, through 200gr's. By and far the Bergers have wholloped the plate WAY more extensively that the others. For a "varmint bullet", I would say they have a darn good chance of anchoring just about anything you wanted to point them at.
Here is another pic I took of it when we were up there a couple weeks back. These were both Bergers as well as Wildcat 210's
If your going with weights under 150grs, then you might stick with just critters, but heavier than that, for deer and just about anything else within reason, I wouldn't have a problem with them.