I use them in my 7MM08, my preference is the 120gn size. They are hard bullets and go through most deer that I have shot.
Here is an article I wrote for another forum that has a pic of a TSX mushroom, the only one I have recovered so far (and I had to dig 14 inches or so into a grassy bank to get it) Note when I washed it up and weighed it- it had retained 100% of its weight.
Fishnhunt fallow story
This Red/ Wapiti hybrid took two in the chest at 30 yards when we roared it in, neither of the TSX bullets exited which illustrates how solid the animals are.
Seeing how they worked on our bigger deer I would have to say they would be impressive on your larger bodied game in the US