Your twist will work fine with this bullet. I feel this bullet will work well on game up to deer size critters but would limit it to this size game. not a terribly stout jacket on these pills. There is enough shear bullet weight to get the job done on deer size game though.
I would avoid shoulder knuckle shots at close range, well any range really, its much easier to punch the lungs anyway.
Starting loads for any conventional jacketed 168 gr bullet will work well. Sierra will probably be the easiest place to get data from. Use the same starting loads for the 168 gr Sierra Matchking and work up from there.
I would say on average you should be in the 3100 fps range with this bullet in your 26" barrel. Maybe a bit more but I like 3100 fps with this bullet weight in the STW.
Another bullet you may want to try is the 169.5 gr ULD RBBT from Wildcat Bullets. This would be better for hunting and at least as high of a BC.
Drop Richard Graves an e-mail at firstname.lastname@example.org
Tell him what you have, what you want to do with it and he will tell you what bullet he recommends.