Yes you can figure out which one will outperform the other with a ballistics program. JBM makes a good one and it is free.
For what it is worth an earlier poster said he compared the two and got very similar downrange performance.
I decided to give it a try. Used the following data: G7 BCs: 168 VLD .316, 180 VLD .337
Elevation 2500 ft with adjusted barometric pressure of 27.32 , temp 65, humidity 30%, scope height 1.5", distance to chronograph 10 ft, wind speed of 10 mph with it moving 90 degrees to bullet flight.
I compared wind drift at 500 and 1000 yds:
Velocity for the 180 was your suggested 2800 fps drift at 500 10.8", at 1000 48.4"
When the 168 was 2940 fps it was VERY close drift at 500 10.7", at 1000 48.6"
I didn't compare drop or retained energy. Feel free to do your own comparisons.