1- I use the Nightforce NXS and I have no problem at all and I hunt with mine both for long range as well as in the woods. I also used this set up on a pack in by horse back hunting trip in Montana a few years ago.
2-I have never ever had one of the NXS knobs turn by accident.
3- A quality tactical scope is as close to bullet proof as an optic can be IMHO
3.5X15X50 on my 300 win
5.5X22X50 on my 338 Lapua
range it,check the wind, dial in correction, aim and only one shot