1- I use the Nightforce NXS and I have no problem at all and I hunt with mine both for long range as well as in the woods. I also used this set up on a pack in by horse back hunting trip in Montana a few years ago.
2-I have never ever had one of the NXS knobs turn by accident.
3- A quality tactical scope is as close to bullet proof as an optic can be IMHO
3.5X15X50 on my 300 win
5.5X22X50 on my 338 Lapua

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range it,check the wind, dial in correction, aim and only one shot