I don't know if the CRF 1600 compensates for inclination angle or not, but there is no mention of that capability in the user manual.
Leica Rangemaster CRF 1600 Manual
I'm not impressed by Leica's idea of ballistic computation either. From the manual they only offer 12 preset trajectories (none user setable) with zeros of 100 or 200 yards (or meters) and a maximum range for the tables of 300 yards (or meters) . What good is that with a rangefinder capable of 1600 yards? None of the 12 trajectories are even close that of my long range or subsonic rifles. I had considered buying a CRF1600 until I read the manual.
I'll keep my Laser Technology impulse 200XL It's reliable to a mile with an inclinometer and serial output to link to a ballistics calculator. Just press the laser trigger. It dumps the range and incination data to the PC when does the caluclation. The rangefinder contains no ballistics tables or computations so it will work with any rifle, cartridge, and bullet. It's disadvantage is that it's about four times heavier than the leica. The advantage is it works.