I have used the 178gr Amax out of a .308 Win to take a Pronghorn at 350yds, Mule Deer at 400yds and Bull Elk at 320yrds. Here are the results.
Pronghorn - Double lung shot, complete pass through with 2" exit. The buck spun around and sprinted about 50 yards before dropping.
Mule Deer - Bullet destroyed the upper lungs and thoracic aorta. The buck never took a step, just stood there for 2-3 seconds before tipping over.
Bull Elk - 1st shot was low in the chest near the heart and took out some major vessels. This was a fatal shot but he was still standing. An immediate follow-up shot dropped the bull. This round went through the scapula penetrated the upper lungs and came to rest just under the hide on the opposite shoulder.
Here is a link with a pic of the bull.
2 desert bulls
At the lower velocities of the .308 Win they have been excellent with good expansion, excellent energy transfer, devastating wound channels and reasonable penetration.