My son his second year of hunting. 6mm Remington 90 gr. Nosler E-tip at 250 yards. One shot and dropped on the spot.
2010 with my son's first elk. 6mm Remington 90 gr. Nosler E-tip at 350 yards. One shot behind her right shoulder and the bullet exited his cow's left shoulder. She went about 25 yards and dropped. He was laying prone using a bi-pod and there was no wind to contest with.
It can vary from animal to animal. It's truely amazing what they can do. I had a buddy shoot a 100 pound antelope buck with his 45-70 with a 405gr. bullet at 150 yards. He hit the buck right behind the shoulder in the lungs. The buck took off and showed no indication of being hit. He ran 100 yards and then dropped.
The 6mm and 243 are great varmint, coyote, deer, and antelope rounds. They promote accurate shooting as they don't beat the shooter up, and they are very effective using bullets such as the Nosler Partition, Accubond, and E-tip. I've probably taken more than 30 antelope, 25 deer, and one spike bull with my own 6mm using 100 gr. Nosler Partitions. I've never felt that the cartridge didn't do its job and never felt like I needed more. I've taken similar game with larger cartridges as well, but the 6mm has worked every time. Yes it's light for elk, but good placement and good bullet means everything.