I agree with CPGfan, the elk below was with a 210 Berger at 200 or 250, cant remember. Many many critters from antelope 60 to 813 yards, deer 100 to 500 yards, Elk 100 to 803. never a problem.
Most recently this black bear with pics of the exit and story here.
My 2011 Black Bear and my 300 WM
Ya know, it doesn't matter what bullet you post and ask about, you will get guys with good and guys with bad experiences. Look at the pics of my bear and decide for yourself.