Hi Troutslayer -
I don't mean to be antagonistic, but "minimizing damage to Coyotes with 300 RUM" is sorta counter-intuitive to me.
That's kinda like having a nitrous-oxide burning V10 on your lawn mower - just enough horsepower to get the job done with maybe a little extra. Maybe.
Otherwise, maybe use a .243 with high SD bullets or something similar?!?
Sorry - i couldn't resist...