I have only experience with the 338 MK's on game, but my experience tells me that they are just the opposite of what has been said here. Instead of being a fragile bullet likely to blow up on the surface of an animal, they were more like FMJ bullets with little to no expansion. However, at extreme long ranges when angle of attack is very steep, they probably have a much bigger tendency to tumble which can be very deadly to game.
If I were to use them again on game (which might happen soon) I would surely aim for bone and forget soft tissue vitals. That way, if they tumble or not, they still break the animal down immediately.
I will say also that their terminal ballistic characteristics (in media) are more inconsistent than any other bullet I have ever tested. But again, this is with the 338 MK which admittedly and obviously has a thicker jacket than the other SMK's.
If it's not far, it's boring.