Case in Point
An exit wound in the off side of a Bull Elk made by a 180 grain bullet fired from a 300 Winn.impact velocity approximately 2600 FPS for 2700 FPE
This exit wound is in the same rib cage of the same Bull Elk,but was made by a 440 grain Flat Point Hard Cast fired from a 500 JRH with a muzzle velocity of 950 FPS for only 888FPE
It is quite aparent that the largest wound (and it was this way start to finish) was made by the least amount of energy..The smaller wound had slightly over 3 times more energy...FPE does not properly predict the outcome,IMHO it is a moot point..As long as your projectile acts as it is designed to do and penetyrates and destroys vital tissue death will occur in short order reguardless of the FPE..Many times a heavier bullet does this better than a lighter bullet of the same caliber even tho the lighter faster bullet has more energy....
range it,check the wind, dial in correction, aim and only one shot