I plan on building a 6.5-06 AI this summer. I plan to drive 130 grain scirroccos at 3200+ FPS from a 28" heavy sporter or light varmint barrel. I like the idea of the AI because I will be forming brass from 25-06 brass and the AI provides a measure of safety because it will not chamber in someones 25-06 by accident.
When you run the numbers on the 6.5 -06 AI with the scirrocco vs the 300 RUM with the 180 or 200 grain accubond the trajectory and wind drift numbers are almost identical to 1000 yards. It is hard to believe that but the 06 case holds its own against the much larger case due to the 6.5, 130 grain BC of .571. Several other 6.5 bullets are equally efficient but the scirrocco offers proven terminal performance. Here is an interesting article on the terminal performance of the 130 grain scirrocco.
Shooting Illustrated's Guns and Hunting - NRA
I would mention that there is a new 140 grain accubond being released this summer that may make a great hunting option also.