Plenty of folks!
The 45 cal 540 gr. with black powder will take anything you want from 5ft to 500 yds no problem. The 45-70 lacks the umph that a 45-110 will deliver at further ranges but in this game, trajectory is the key issue since the rounds travel at 1300-1400 fps. Go to the Shiloh Sharps website/forum and you will find a wealth of info.