I zero my 7mm at 300 yards. This gives the ability to take a quick shot if presented and I know that from the muzzle to a litle over 400 yards I'm never more than 2.5" high or low. On a big game animal this works. Having said this, I still dial for all shots over 300 yards.
This gun, using the NF 5.5-22x56 gives me a setup, zeroed at 300 that allows me to use the 1st, hash at 400, 2nd. hash at 500, 3rd. hash at 600 and 4th. hash at 700 and I can break clay pigeons when playing just by using the reticle. But, when hunting and given the time to do so, I'll always dial for the distance/elevation.;)