You are absolutely right on the 375 CT component pricing (though the CT brass is now $2.15 ea) - very reasonable for such a high-performing, ELR cartidge. On the other hand, it is hard to understand how CT can sell loaded ammo (with 350 SMK)at $7.10 each when component cost is $2.15/case + less than $1/SMK + less than 5 cents/primer (Federal red box) + at most $0.50 for powder --- in total less than $3.70/round). That's min $68 to load and package one 20 round box. OUCH! Definitely reload!
The power level (Muzzle Energy) can also be close to a 416 Barrett - using the CT estm velocity of 3200 (https://cheytac.com/ammunition/375350-gr-smk-cartridge/
) that's 7960 vs Barrett's published data (Barrett | Ammunition
) for their 398 gr projectile of 7952-8767 (depending on barrel length and platform).
The above noted, I suspect that Dave Viers will quote you better numbers (than the Barrett) for his 416 VM and better numbers (than the "factory" 375 CT) for his 375 VM2.
Also, IF you have not already invested in an action (conventional style), CT-class are quite a bit less than 50 BMG (required for 416 Barrett) - BAT lists their CT at $1250 vs $2300 for the EX 2.0. [NOTE: Those are single shot action prices since BAT does not currently build a CT- or BMG-capable repeater. Single shot, shell-holder-style BMG actions are half the price or less than a BAT.]
Bottom line, go 375, or a CT-based 338. Now the question is "Which one?" A whole nother thread - done repeatedly here and elsewhere.